Early-Stage Researcher (m/f/d) in cooperation with BIOREMIA (ESR15) in Schönkirchen at Stryker Corporation

Date Posted: 2/9/2020

Job Snapshot

Job Description



Project Description

This ESR position is part of the European Training Network “BIOREMIA” dealing with research on novel biofilm-resistant materials for hard tissue implant applications. BIOREMIA offers the possibility to pursue the PhD within the Network at different universities and industrial companies from 10 European countries (Germany, Austria, Italy, Sweden, Greece, UK, Spain, Ireland, France, and Switzerland). Background information on all ESR positions and BIOREMIA Network is available on www.bioremia.eu BIOREMIA (“BIOfilm-REsistant Materials for hard tissue Implant Applications”) is funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 861046.

Application deadline: 31/03/2020

Expected starting date: 1 April 2020 (approx.)

Job/project description

Objectives

Optimisation of industrially standardized coating technologies for metallic materials in clinical use and for new beta-type TiNb alloys towards a) improved antibacterial efficiency, and b) suitable osseointegration for trauma implants.

Tasks

1) To produce test implants based on TiAlV, Stainless steel and TiNb,

2) Coat these implants using anodization Type II and III as well as biodegradable HA;

3) Biomechanical tests and surface analytics;

4) Differential adhesion of fibroblasts, osteoblasts and other osteo-related cells will be described in in vitro assays and inflammatory biomarkers will be screened (secondment);

5) The antimicrobial effect of the coating will be characterized in comparison to the raw (uncoated) material using microbiological tests (secondment);

6) Initiating of the regulatory assessment of antibacterial coatings, verification and validation protocols and feasibility studies on the transfer of antibacterial coating technologies into qualified manufacturing processes.

Expected Results

Understanding the impact of coating of bone implants for the complex mechanism of osseointegration at the surface to the tissue Development of new standard antibacterial surfaces for metallic implants for traumatological applications; Enable the ESR to develop entrepreneurial thinking and methods in industry-led R&D comprising prototype development and scale-up of coating technologies as well as managerial, leadership and team skills in an international and industrial environment

The ESR will travel abroad for research secondments at different institutions of the BIOREMIA Network (e.g. at Goeteborgs Universitet - Sweden, IFW Dresden - Germany, University of Cambridge-UK, The University Clinics of Giessen & Marburg - Germany). The ESR will enroll in the doctoral student programme at Goeteborgs Universitet, Sweden. Appointment The appointment will be on a temporary basis for a maximum period of 36 months (PhD student, regular full-time employment contract), with an attractive salary plus allowances package according to the Marie Skłodowska-Curie / Innovative Training Networks rules.

Eligibility conditions

Applicants must at the time of recruitment

1) Be in the first four years (full-time equivalent) of their research careers

2) Have not resided in Germany for more than 12 months in the last 3 years

3) Have not been awarded a doctoral degree

Candidate’s profile

  • Applicants must hold a Master’s degree or equivalent in Materials Science and Engineering or Biomedical engineering or other domains related to the core activities described above providing access to PhD programs and should have experience with experimental research.
  • Applicants must have excellent proficiency in written and spoken English
  • Applicants must have strong motivation and ability to collaborate in an interdisciplinary and international team
  • Good command of German language will be a plus
  • Competences in materials science and biomaterials will be a plus.

Contact

We’re looking forward to your online application including your salary expectations and all relevant documents (cover letter, current CV, certificates). Please note during our application process to upload all attachments directly under the item "CV".

If you have any questions, please don´t hesitate to contact Silvia Soethe on +49 (0) 4348 702 193.

We are looking forward to your application! Please notice that the title of this advertisement can differ from the internal position title.

Further information

Some background material about host institution can be found here: www.bioremia.eu

Work From Home: Occasional

Travel Percentage: 20%

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